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Cranberry

Cranberry-1

The food industry considers the nutrient content and antioxidant properties of the cranberry a sufficient reason to give them the commercial status of being a novel "superfruit." Their use and consumption has not significantly changed over the years with most people consuming the largest amounts either fresh or canned as sauce in a jellied or whole berry form during the Thanksgiving and Christmas holidays.

The juice is more regularly consumed by individuals that consider the berry to be a potent free radical scavenger (antioxidant) of the blood and as a means of treating urinary tract infections.

Vitamins, Minerals and Phytochemical Components

The berries are a source of polyphenol antioxidants, which are phytochemicals being currently researched for their possible beneficial effects of the cardiovascular system, immune system, and as anticarcinogenic properties. They are a particularly rich source of phenolic phytochemicals that include: phenolic acids (benzoic, hydroxycinnamic, and ellagic acids) and flavonoids (anthocyanins, flavonols, and flavan-3-ols) (1).

Their seed oil has been found to contain higher levels of tocotrienols than any other fruits. Tocotrienol is an antioxidant composed of vitamin E that stabilizes cell membranes, regulates oxidative stress, and protects polyunsaturated fatty acids and vitamin A from free radical damage (2).

Medicinal Uses Based on Scientific Studies

Current research shows that the cranberry is beneficial for the treatment of urinary tract bacterial infections (3). Studies suggest that a component of the juice competitively inhibits bacterial attachment to the bladder and urethra, which allows the bacteria to be flushed out more easily.

Recent studies have been performed where cranberry was administered in a capsule form to patients suffering from urinary tract infections. The results showed that the berry has antibacterial properties that lead to the inhibition of Escherichia coli (E. coli) infections by reducing the bacteria’s ability to attach itself to cells. This study also suggests that the consumption of the juice may be an effective treatment for urinary tract infections (4).

The juice also contains a chemical component made up of a high molecular weight non-dializable material (NDM), that can inhibit and even reverse plaque formation from Streptococcus mutan bacteria that cause tooth decay and other oral bacteria that cause gingivitis.

The raw berries are the most plentiful source of the anthocyanidin flavonoid peonidin, and they are also rich in two other anthocyanidins, cyanidin and petunidin. Although these anthocyanidins are unusually powerful at inhibiting and even killing many kinds of human cancer cells in laboratory studies, when ingested by humans their effect is unproven and significant questions about their success are raised by their poor absorption into somatic cells and their rapid elimination from the bloodstream.

These potent berries also contain tannins, which have anti-clotting properties. Current evidence also shows that polyphenols found in them may reduce the risk of developing cardiovascular disease by increasing the resistance of low-density lipoprotein (LDL), known as bad cholesterol, to oxidation, inhibiting platelet aggregation, reducing blood pressure, and by having anti-thrombotic and anti-inflammatory effects on the body (1).

References

1. Cranberry health research summary. (2000) International Conference and Exhibit on Nutraceuticals and Functional Foods. University of Massachusetts-Amherst. Retrieved on January 24 2008 from http://www.cranberryinstitute.org/news/pr/pr022001.htm

2. Dugoua JJ, Seely D, Perri D, Mills E, Koren G. (2008) Safety and efficacy of cranberry (vaccinium macrocarpon) during pregnancy and lactation. The Canadian Journal of Clinical Pharmacology, 15(1):e80-6.

3. Lavigne JP, Bourg G, Combescure C, Botto H, Sotto A. (2008) In-vitro and in-vivo evidence of dose-dependent decrease of uropathogenic Escherichia coli virulence after consumption of commercial Vaccinium macrocarpon (cranberry) capsules. Clinical Microbiology and Infection, 2008 Jan 7 [Epub ahead of print]

4. McKay DL, Blumberg JB. (2007) Cranberries (Vaccinium macrocarpon) and cardiovascular disease risk factors. Nutrion Reviews, 65(11):490-502.

Cranberry Nutrition Table

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